CCRM operates its current Good Manufacturing Practices (cGMP) facility, the Centre for Cell and Vector Production (CCVP), in partnership with the University Health Network (UHN). This facility is designed to be compliant with Health Canada, United States Food and Drug Administration (USFDA) and European Medicines Agency (EMA) for early phase materials in the cell and gene therapy markets. CCVP manufactures materials to support Phase I/II in-human clinical trials. Our cGMP facility assists with the transfer to clients’ manufacturing facilities or to a contract manufacturing organization (CMO).

Inside CCVP you will find:

  • 10 class B clean rooms
  • cryogenic storage
  • a cell irradiator
  • an in-house quality control (QC) laboratory
  • a robust quality management system
  • specialized cell processing hardware

Services offered in CCVP

Services offered in CCVP include full manufacturing and release of cell and viral vector materials, QC testing, access to clean rooms, cell bank creation, training services, supplier management and audit support services.

CCRM’s expertise in manufacturing cell and gene therapies includes the following areas:

  • cGMP manufacturing of master/working cell banks
  • cGMP manufacturing of cell and gene therapies for Phase I & II clinical trials

CCVP Features:

  • Positive and negative pressure clean rooms for cell and viral production
  • Facilities for QC and quality assurance (QA) activities
  • Two vector production suites, each measuring 260 ft² (~24 m²)
  • Eight clean room suites, from 237 ft² (~22 m²) to 301 ft² (~28 m²)

To learn more about CCVP, download a two-page information resource.

MarsDD Building

CCRM’s state of-the-art facility is located in downtown Toronto within the MaRS Discovery District.